EBRU EFEM

EBRU EFEM

04 September 2023 Monday


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Coronavirüs ve Gözler

<strong>Coronavirüs ve Gözler</strong>
0

BEĞENDİM

ABONE OL

2019’dan bu yana, küresel koronavirüs (COVID-19) pandemisinden hayatlarımız büyük ölçüde etkilendi. Koronavirüs, yüksek oranda bulaşıcı ve şiddetli akut solunum sendromuna neden olmakta. Dünya Sağlık Örgütüne göre, dünya çapında altı milyondan fazla ölüm Koronavirüs pandemisiyle bağlantılı.

Göze etkileri

Son literatürde, COVID-19 hastalarında oküler bulgu prevalansı %2-32 arasında değişmektedir.

Virüsün, gözün farklı bölgelerini hafif ila şiddetli etkileyebildiği görüldü.

COVID-19 hastalarında en sık görülen göz bulgusu konjonktivitti. Belirtileri arasında göz kızarıklığı, göz tahrişi, göz ağrısı, sulanma, mukus akıntısı ve göz kapağı şişmesi sayılabilir. Bu belirtilerin en yaygın olanı ise şiddetli sistemik COVID-19 belirtileri olan hastalarda bulundu. Oküler yüzeyin ötesinde, birkaç akut ön üveit vakası da bildirilmiştir.

COVID-19 virüsünün vasküler (retina etkisi), enflamatuar (iris iltihabı) ve nöronal etiyolojilerle ilgili arka göz komplikasyonlarına neden olduğu da gözlemlenmiştir. Bazı araştırmalar, viral parçacıklar içeren retina hücrelerinde COVID-19 proteinlerinin varlığını da göstermektedir. Bazı vakalarda ise sistemik vasküler risk faktörü olmayan görme kaybına neden olan santral retinal ven ve arter tıkanıklıkları (vakadan vakaya değişir) gözlenmiştir. Diğer rahatsızlıklar arasında Optik nörit (optik sinir iltihabı) ve papilloödem (optik sinirin şişmesi) ve hemorajileri içerir.

COVID-19’un gözü uzun vadede nasıl etkilediğini görmek ilginç olacak. Gelecekteki araştırmalar ve vaka çalışmaları, COVID-19 ve komplikasyonları hakkındaki bilgimizi artıracaktır.

ENGLISH

Coronavirus and Eyes

Since 2019, our lives have been drastically impacted with the global coronavirus (COVID-19) pandemic. Coronavirus causes highly transmissible severe acute respiratory syndrome. According to the World Health Organisation, over six million deaths has been linked to the Coronavirus pandemic worldwide.

In the recent literature, the prevalence of ocular manifestation ranged from 2%-32% in patients with COVID-19. It has been shown that the virus can affect different parts of the eye, with mild to severe presentations.

The most common ocular finding in patient with COVID-19 was conjunctivitis. Symptoms include eye redness, eye irritation, eye soreness, tearing, mucous discharge and eye lid swelling. These symptoms were most commonly found in patients with severe systemic symptoms of COVID-19. Beyond the ocular surface, several cases of acute anterior uveitis have also been reported.

The COVID-19 virus has been observed to cause posterior eye complications related to vascular, inflammatory and neuronal aetiologies. Some research supports the presence of COVID-19 proteins in retinal cells containing viral particles. Central retinal vein and artery occlusions resulting in vision loss (severity varies case by case) have been observed in some patients with no other systemic vascular risk factors. Other posterior eye involvement includes optic neuritis (inflammation of the optic nerve) and papilloedema (swelling of the optic nerve) and haemorrhages.

It will be interesting to see how COVID-19 impacts the eye long-term. Future research and case studies will improve our knowledge on COVID-19 and its complications.

References:

Soltani S, Tabibzadeh A, Zakeri A, Zakeri AM, Latifi T, Shabani M, Pouremamali A, Erfani Y, Pakzad I, Malekifar P, Valizadeh R, Zandi M, Pakzad R. COVID-19 associated central nervous system manifestations, mental and neurological symptoms: a systematic review and meta-analysis. Rev Neurosci. 2021 Apr 27;32(3):351-361

Araujo-Silva CA, Marcos AAA, Marinho PM, Branco AMC, Roque A, Romano AC, Matuoka ML, Farah M, Burnier M, Moraes NF, Tierno PFGMM, Schor P, Sakamoto V, Nascimento H, de Sousa W, Belfort R. Presumed SARS-CoV-2 Viral Particles in the Human Retina of Patients With COVID-19. JAMA Ophthalmol. 2021 Sep 01;139(9):1015-1021.